The unmanned Exploration Flight Test 1 mission, the maiden flight of NASA’s Orion spacecraft, is due to lift off atop a Delta IV rocket from Cape Canaveral during a two-hour, 39-minute window which opens at 12:05 UTC 07:05 local time. [7:05 AM Eastern]
Thursday’s mission will see Orion make two orbits of the planet during a four and a half hour mission that will end with the spacecraft’s recovery in the Pacific Ocean. Reaching a maximum altitude of 5,790 kilometres [3,600 miles] the mission will test separation mechanisms, demonstrate Orion’s Crew Module in orbit and prove that the spacecraft can withstand atmospheric reentry and be recovered successfully.
via EFT-1 Orion preparing for historic launch atop of Delta IV-H | NASASpaceFlight.com.
http://www.nasa.gov/multimedia/nasatv will cover the launch, orbits, and re-entry. Should be a good test of the heatshield during re-entry. For comparison, the International Space Station flies at an altitude of around 250 miles.

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